Maybe this can work:
public static bool IsProgramRunning(string TitleOfYourForm)
{
bool result = false;
Process[] processes = Process.GetProcesses();
foreach (Process p in processes)
{
if (p.MainWindowTitle.Contains(TitleOfYourForm))
{
result = true;
break;
}
}
return result;
}
Call this function in the Main function(before opening the mainForm), if it is false Application.Exit() else show your form..
If this answer helped you, vote me.