Assigning prototype methods *inside* the constructor function – why not?

Functionally, are there any drawbacks to structuring my code this way?
Will adding a prototypical method to a prototype object inside the
constructor function’s body (i.e. before the constructor function’s
expression statement closes) cause unexpected scoping issues?

Yes, there are drawbacks and unexpected scoping issues.

1. Assigning the prototype over and over to a locally defined function, both repeats that assignment and creates a new function object each time. The earlier assignments will be garbage collected since they are no longer referenced, but it’s unnecessary work in both runtime execution of the constructor and in terms of garbage collection compared to the second code block.

2. There are unexpected scoping issues in some circumstances. See the Counter example at the end of my answer for an explicit example. If you refer to a local variable of the constructor from the prototype method, then your first example creates a potentially nasty bug in your code.

There are some other (more minor) differences. Your first scheme prohibits the use of the prototype outside the constructor as in:

Filter.prototype.checkProduct.apply(someFilterLikeObject, ...)

And, of course, if someone used:

Object.create(Filter.prototype) 

without running the Filter constructor, that would also create a different result which is probably not as likely since it’s reasonable to expect that something that uses the Filter prototype should run the Filter constructor in order to achieve expected results.

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From a run-time performance point of view (performance of calling methods on the object), you would be better off with this:

var Filter = function( category, value ){
  this.category = category;
  this.value = value;

  // product is a JSON object
  this.checkProduct = function( product ){
    // run some checks
    return is_match;
  }

};

There are some Javascript “experts” who claim that the memory savings of using the prototype is no longer needed (I watched a video lecture about that a few days ago) so it’s time to start using the better performance of methods directly on the object rather than the prototype. I don’t know if I’m ready to advocate that myself yet, but it was an interesting point to think about.

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The biggest disadvantage of your first method I can think of is that it’s really, really easy to make a nasty programming mistake. If you happen to think you can take advantage of the fact that the prototype method can now see local variables of the constructor, you will quickly shoot yourself in the foot as soon as you have more than one instance of your object. Imagine this circumstance:

var Counter = function(initialValue){
  var value = initialValue;

  // product is a JSON object
  Counter.prototype.get = function() {
      return value++;
  }

};

var c1 = new Counter(0);
var c2 = new Counter(10);
console.log(c1.get());    // outputs 10, should output 0

Demonstration of the problem: http://jsfiddle.net/jfriend00/c7natr3d/

This is because, while it looks like the get method forms a closure and has access to the instance variables that are local variables of the constructor, it doesn’t work that way in practice. Because all instances share the same prototype object, each new instance of the Counter object creates a new instance of the get function (which has access to the constructor local variables of the just created instance) and assigns it to the prototype, so now all instances have a get method that accesses the local variables of the constructor of the last instance created. It’s a programming disaster as this is likely never what was intended and could easily be a head scratcher to figure out what went wrong and why.