Efficient way to find missing elements in an integer sequence

If the input sequence is sorted, you could use sets here. Take the start and end values from the input list:

def missing_elements(L):
    start, end = L[0], L[-1]
    return sorted(set(range(start, end + 1)).difference(L))

This assumes Python 3; for Python 2, use xrange() to avoid building a list first.

The sorted() call is optional; without it a set() is returned of the missing values, with it you get a sorted list.

Demo:

>>> L = [10,11,13,14,15,16,17,18,20]
>>> missing_elements(L)
[12, 19]

Another approach is by detecting gaps between subsequent numbers; using an older itertools library sliding window recipe:

from itertools import islice, chain

def window(seq, n=2):
    "Returns a sliding window (of width n) over data from the iterable"
    "   s -> (s0,s1,...s[n-1]), (s1,s2,...,sn), ...                   "
    it = iter(seq)
    result = tuple(islice(it, n))
    if len(result) == n:
        yield result    
    for elem in it:
        result = result[1:] + (elem,)
        yield result

def missing_elements(L):
    missing = chain.from_iterable(range(x + 1, y) for x, y in window(L) if (y - x) > 1)
    return list(missing)

This is a pure O(n) operation, and if you know the number of missing items, you can make sure it only produces those and then stops:

def missing_elements(L, count):
    missing = chain.from_iterable(range(x + 1, y) for x, y in window(L) if (y - x) > 1)
    return list(islice(missing, 0, count))

This will handle larger gaps too; if you are missing 2 items at 11 and 12, it’ll still work:

>>> missing_elements([10, 13, 14, 15], 2)
[11, 12]

and the above sample only had to iterate over [10, 13] to figure this out.