One way which seems to work (at least in 0.10.1 and 0.11.0.dev-fc8de6d):
>>> !cat ragged.csv
1,2,3
1,2,3,4
1,2,3,4,5
1,2
1,2,3,4
>>> my_cols = ["A", "B", "C", "D", "E"]
>>> pd.read_csv("ragged.csv", names=my_cols, engine="python")
A B C D E
0 1 2 3 NaN NaN
1 1 2 3 4 NaN
2 1 2 3 4 5
3 1 2 NaN NaN NaN
4 1 2 3 4 NaN
Note that this approach requires that you give names to the columns you want, though. Not as general as some other ways, but works well enough when it applies.