Only magic_quoted_runtime can be disabled at runtime. But magic_quotes_gpc can’t be disabled at runtime (PHP_INI_ALL changable until PHP 4.2.3, since then PHP_INI_PERDIR); you can only remove them:
if (get_magic_quotes_gpc()) {
$process = array(&$_GET, &$_POST, &$_COOKIE, &$_REQUEST);
while (list($key, $val) = each($process)) {
foreach ($val as $k => $v) {
unset($process[$key][$k]);
if (is_array($v)) {
$process[$key][stripslashes($k)] = $v;
$process[] = &$process[$key][stripslashes($k)];
} else {
$process[$key][stripslashes($k)] = stripslashes($v);
}
}
}
unset($process);
}
For further information see Disabling Magic Quotes.