How can I use a Python script in the command line without cd-ing to its directory? Is it the PYTHONPATH?

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I think you’re a little confused. PYTHONPATH sets the search path for importing python modules, not for executing them like you’re trying.

PYTHONPATH Augment the default search path for module files. The
format is the same as the shell’s PATH: one or more directory
pathnames separated by os.pathsep (e.g. colons on Unix or semicolons
on Windows). Non-existent directories are silently ignored.

In addition to normal directories, individual PYTHONPATH entries may
refer to zipfiles containing pure Python modules (in either source or
compiled form). Extension modules cannot be imported from zipfiles.

The default search path is installation dependent, but generally
begins with prefix/lib/pythonversion (see PYTHONHOME above). It is
always appended to PYTHONPATH.

An additional directory will be inserted in the search path in front
of PYTHONPATH as described above under Interface options. The search
path can be manipulated from within a Python program as the variable
sys.path.

http://docs.python.org/2/using/cmdline.html#envvar-PYTHONPATH

What you’re looking for is PATH. 

export PATH=$PATH:/home/randy/lib/python

However, to run your python script as a program, you also need to set a shebang for Python in the first line. Something like this should work:

#!/usr/bin/env python

And give execution privileges to it:

chmod +x /home/randy/lib/python/gbmx.py

Then you should be able to simply run gmbx.py from anywhere.

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