How should I store GUID in MySQL tables?

My DBA asked me when I asked about the best way to store GUIDs for my objects why I needed to store 16 bytes when I could do the same thing in 4 bytes with an Integer. Since he put that challenge out there to me I thought now was a good time to mention it. That being said…

You can store a guid as a CHAR(16) binary if you want to make the most optimal use of storage space.

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