You can declare unique constraints using the @Table(uniqueConstraints = ...)
annotation in your entity class, i.e.
@Entity
@Table(uniqueConstraints={
@UniqueConstraint(columnNames = {"productId", "serial"})
})
public class InventoryItem {
...
}
Note that this does not magically create the unique constraint in the database, you still need a DDL for it to be created. But seems like you are using some sort of automated tool for creating the database based on JPA entity definitions.