If you have an NSImage and want to save it as an image file to the filesystem, you should never use lockFocus! lockFocus creates a new image which is determined for getting shown an the screen and nothing else. Therefore lockFocus uses the properties of the screen: 72 dpi for normal screens and 144 dpi for retina screens. For what you want I propose the following code:
+ (void)saveImage:(NSImage *)image atPath:(NSString *)path {
CGImageRef cgRef = [image CGImageForProposedRect:NULL
context:nil
hints:nil];
NSBitmapImageRep *newRep = [[NSBitmapImageRep alloc] initWithCGImage:cgRef];
[newRep setSize:[image size]]; // if you want the same resolution
NSData *pngData = [newRep representationUsingType:NSPNGFileType properties:nil];
[pngData writeToFile:path atomically:YES];
[newRep autorelease];
}