To make Process.Start use exec directly instead of using the OS’ mechanism for opening files, you must set UseShellExecute to false. This is also true on Linux and Windows.
Process.Start(new ProcessStartInfo (
"/Applications/Google Chrome.app/Contents/MacOS/Google Chrome",
"--no-first-run")
{ UseShellExecute = false });
Note that you can also use ‘open’ for your use case, to run the Chrome app bundle properly. Use the ‘-a’ argument to force it to run a specific app, the ‘-n’ argument to open a new instance, and ‘–args’ to pass in arguments:
Process.Start(new ProcessStartInfo (
"open",
"-a '/Applications/Google Chrome.app' -n --args --no-first-run")
{ UseShellExecute = false });