MySQL remove all whitespaces from the entire column

To replace all spaces :

UPDATE `table` SET `col_name` = REPLACE(`col_name`, ' ', '')

To remove all tabs characters :

UPDATE `table` SET `col_name` = REPLACE(`col_name`, '\t', '' )

To remove all new line characters :

UPDATE `table` SET `col_name` = REPLACE(`col_name`, '\n', '')

http://dev.mysql.com/doc/refman/5.0/en/string-functions.html#function_replace

To remove first and last space(s) of column :

UPDATE `table` SET `col_name` = TRIM(`col_name`)

http://dev.mysql.com/doc/refman/5.0/en/string-functions.html#function_trim

and if you want remove all type of spaces, you can combine all of this functions :

UPDATE `table` SET `col_name` = REPLACE(REPLACE(REPLACE(`col_name`, ' ', ''), '\t', ''), '\n', '');

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