Pandas how to apply multiple functions to dataframe

For Pandas 0.20.0 or newer, use df.agg (thanks to ayhan for pointing this out):

In [11]: df.agg(['mean', 'std'])
Out[11]: 
           one       two
mean  5.147471  4.964100
std   2.971106  2.753578

For older versions, you could use

In [61]: df.groupby(lambda idx: 0).agg(['mean','std'])
Out[61]: 
        one               two          
       mean       std    mean       std
0  5.147471  2.971106  4.9641  2.753578

Another way would be:

In [68]: pd.DataFrame({col: [getattr(df[col], func)() for func in ('mean', 'std')] for col in df}, index=('mean', 'std'))
Out[68]: 
           one       two
mean  5.147471  4.964100
std   2.971106  2.753578