Sublime text3 and virtualenvs

Hopefully this is along the lines you are imagining. I attempted to simplify my solution and remove some things you likely do not need.

The advantages of this method are:

• Single button press to launch a SublimeREPL with correct interpreter and run a file in it if desired.
• After setting the interpreter, no changes or extra steps are necessary when switching between projects.
• Can be easily extended to automatically pick up project specific environment variables, desired working directories, run tests, open a Django shell, etc.

Let me know if you have any questions, or if I totally missed the mark on what you’re looking to do.

Set Project’s Python Interpreter

1. Open our project file for editing:

    Project -> Edit Project
   

2. Add a new key to the project’s settings that points to the desired virtualenv:

    "settings": {
        "python_interpreter": "/home/user/.virtualenvs/example/bin/python"
    }
   

A "python_interpreter" project settings key is also used by plugins like Anaconda.

Create plugin to grab this setting and launch a SublimeREPL

1. Browse to Sublime Text’s Packages directory:

   Preferences -> Browse Packages...
   

2. Create a new python file for our plugin, something like: project_venv_repls.py

3. Copy the following python code into this new file:

   import sublime_plugin
   
   
   class ProjectVenvReplCommand(sublime_plugin.TextCommand):
       """
       Starts a SublimeREPL, attempting to use project's specified
       python interpreter.
       """
   
       def run(self, edit, open_file="$file"):
           """Called on project_venv_repl command"""
           cmd_list = [self.get_project_interpreter(), '-i', '-u']
   
           if open_file:
               cmd_list.append(open_file)
   
           self.repl_open(cmd_list=cmd_list)
   
       def get_project_interpreter(self):
           """Return the project's specified python interpreter, if any"""
           settings = self.view.settings()
           return settings.get('python_interpreter', '/usr/bin/python')
   
       def repl_open(self, cmd_list):
           """Open a SublimeREPL using provided commands"""
           self.view.window().run_command(
               'repl_open', {
                   'encoding': 'utf8',
                   'type': 'subprocess',
                   'cmd': cmd_list,
                   'cwd': '$file_path',
                   'syntax': 'Packages/Python/Python.tmLanguage'
               }
           )
   

Set Hotkeys

1. Open user keybind file:

    Preferences -> Key Bindings - User
   

2. Add a few keybinds to make use of the plugin. Some examples:

    // Runs currently open file in repl
    {
        "keys": ["f5"],
        "command": "project_venv_repl"
    },
    // Runs repl without any file
    {
        "keys": ["f6"],
        "command": "project_venv_repl",
        "args": {
            "open_file": null
        }
    },
    // Runs a specific file in repl, change main.py to desired file
    {
        "keys": ["f7"],
        "command": "project_venv_repl",
        "args": {
            "open_file": "/home/user/example/main.py"
        }
    }