Trying to solve symmetric difference using Javascript

As with all problems, it’s best to start off writing an algorithm:

Concatenate versions of the arrays, where each array is filtered to contain those elements which no array other than the current one contains

Then just write that down in JS:

function sym() {
  var arrays = [].slice.apply(arguments);

  return [].concat.apply([],               // concatenate
    arrays.map(                            // versions of the arrays
      function(array, i) {                 // where each array
        return array.filter(               // is filtered to contain
          function(elt) {                  // those elements which
            return !arrays.some(           // no array
              function(a, j) {             // 
                return i !== j             // other than the current one
                  && a.indexOf(elt) >= 0   // contains
                ;
              }
            );
          }
        );
      }
    )
  );
}

Non-commented version, written more succinctly using ES6:

function sym(...arrays) {
  return [].concat(arrays . 
    map((array, i) => array . 
      filter(elt => !arrays . 
        some((a, j) => i !== j && a.indexOf(elt) >= 0))));
}