This is the easy way to bind the DataGridTextColumn header to the data context:
<DataGrid x:Name="summaryGrid" Grid.Row="3" AutoGenerateColumns="False" IsReadOnly="True" CanUserAddRows="False">
<DataGrid.Columns>
<DataGridTextColumn Header="Hard Coded Title" Width="*"/>
<DataGridTextColumn Width="100">
<DataGridTextColumn.Header>
<TextBlock Text="{Binding DataContext.SecondColumnTitle,
RelativeSource={RelativeSource AncestorType={x:Type local:MainWindow}}}"/>
</DataGridTextColumn.Header>
</DataGridTextColumn>
<DataGridTextColumn Width="150">
<DataGridTextColumn.Header>
<TextBlock Text="{Binding DataContext.ThirdColumnTitle,
RelativeSource={RelativeSource AncestorType={x:Type local:MainWindow}}}"/>
</DataGridTextColumn.Header>
</DataGridTextColumn>
</DataGrid.Columns>
</DataGrid>
You will obviously need to have properties: SecondColumnTitle
and ThirdColumnTitle
implemented on your data context class.
I have this solution working in .net 4.5 and did not have a chance nor reason to try it in earlier versions of the framework.