This fix from apple dev forums works for me. I have had performance/autocomplete issues since beta 5 i think and now xcode 6.1/Yosemite on my old 2010 MBP is working flawlessly.
- Quit Xcode.
- Restart the computer (this is to clear any in-memory caches).
- Delete the contents of the DerivedData folder
(~/Library/Developer/Xcode/DerivedData) - [This is the key move:] Delete ~/Library/Caches/com.apple.dt.Xcode.
Now launch Xcode once more…