Get instance of Excel application with C# by Handle

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Use the following code to get the first running instance of Excel:

oExcelApp =  (Excel.Application)System.Runtime.InteropServices.Marshal.GetActiveObject("Excel.Application");

Example

public Excel.Application StartExcel()
{
    Excel.Application instance = null;
    try
    {
       instance = (Excel.Application)System.Runtime.InteropServices.Marshal.GetActiveObject("Excel.Application");
    }
    catch (System.Runtime.InteropServices.COMException ex)
    {
       instance = new Excel.ApplicationClass();
    }

    return instance;
}

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