How can I remove all duplicates so that NONE are left in a data frame?

This will extract the rows which appear only once (assuming your data frame is named df):

df[!(duplicated(df) | duplicated(df, fromLast = TRUE)), ]

How it works: The function duplicated tests whether a line appears at least for the second time starting at line one. If the argument fromLast = TRUE is used, the function starts at the last line.

Boths boolean results are combined with | (logical ‘or’) into a new vector which indicates all lines appearing more than once. The result of this is negated using ! thereby creating a boolean vector indicating lines appearing only once.

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