Mac OS: /usr/bin/env: bad interpreter: Operation not permitted

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Did you happen to open/save the file in TextEdit?

That can introduce filesystem metadata (quarantine attribute) leading to the symptom you describe.

Try:

xattr -l /usr/local/bin/bbcolors

and

xattr -d com.apple.quarantine /usr/local/bin/bbcolors

if you see the quarantine attribute.

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