How about:
import numpy as np
a = np.array([[[10, 1, 1, 2],
[2, 2, 2, 3],
[3, 3, 3, 4]],
[[1, 1, 1, 2],
[2, 2, 2, 3],
[3, 3, 3, 4]]])
and the reverse along the last dimension is:
b = a[:,:,::-1]
or
b = a[...,::-1]
although I like the later less since the first two dimensions are implicit and it is more difficult to see what is going on.