Prevent multiple instances of a given app in .NET?

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Use Mutex. One of the examples above using GetProcessByName has many caveats. Here is a good article on the subject:

http://odetocode.com/Blogs/scott/archive/2004/08/20/401.aspx

[STAThread]
static void Main() 
{
   using(Mutex mutex = new Mutex(false, "Global\\" + appGuid))
   {
      if(!mutex.WaitOne(0, false))
      {
         MessageBox.Show("Instance already running");
         return;
      }

      Application.Run(new Form1());
   }
}

private static string appGuid = "c0a76b5a-12ab-45c5-b9d9-d693faa6e7b9";

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