You have to be very careful about the method names. In this case, the method name is just “lowercaseString“, not “lowercaseString:” (note the absence of the colon). That’s why you’re getting NO returned, because NSString objects respond to the lowercaseString message but not the lowercaseString: message.
How do you know when to add a colon? You add a colon to the message name if you would add a colon when calling it, which happens if it takes one argument. If it takes zero arguments (as is the case with lowercaseString), then there is no colon. If it takes more than one argument, you have to add the extra argument names along with their colons, as in compare:options:range:locale:.
You can also look at the documentation and note the presence or absence of a trailing colon.