Translate Rectangle Position in Zoom Mode Picturebox

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You can translate selected rectangle on the picture box to the rectangle on image this way:

public RectangleF GetRectangeOnImage(PictureBox p, Rectangle selectionRect)
{
    var method = typeof(PictureBox).GetMethod("ImageRectangleFromSizeMode",
        System.Reflection.BindingFlags.NonPublic | System.Reflection.BindingFlags.Instance);
    var imageRect = (Rectangle)method.Invoke(p, new object[] { p.SizeMode });
    if (p.Image == null)
        return selectionRect;
    var cx = (float)p.Image.Width / (float)imageRect.Width;
    var cy = (float)p.Image.Height / (float)imageRect.Height;
    var r2 = Rectangle.Intersect(imageRect, selectionRect);
    r2.Offset(-imageRect.X, -imageRect.Y);
    return new RectangleF(r2.X * cx, r2.Y * cy, r2.Width * cx, r2.Height * cy);
}

Note: You can find ImageRectangleFromSizeMode method source code here and use it as write such method as part of your application code.

Example – Crop Image of PictureBox having SizeMode = Zoom

As an example, the following code will crop the given rectangle of the picture box 1 and will set the result as image of picture box 2:

var selectedRectangle = new Rectangle(7, 30, 50, 40);
var result = GetRectangeOnImage(pictureBox1, selectedRectangle);
using (var bm = new Bitmap((int)result.Width, (int)result.Height))
{
    using (var g = Graphics.FromImage(bm))
        g.DrawImage(pictureBox1.Image, 0, 0, result, GraphicsUnit.Pixel);
    pictureBox2.Image = (Image)bm.Clone();
}

Here is the input image:

enter image description here

And this is the result:

enter image description here

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