Using pandas new styling functionality (since 0.17.1):
import numpy as np
import pandas as pd
arrays = [['Midland', 'Midland', 'Hereford', 'Hereford', 'Hobbs','Hobbs', 'Childress',
'Childress', 'Reese', 'Reese', 'San Angelo', 'San Angelo'],
['WRF','MOS','WRF','MOS','WRF','MOS','WRF','MOS','WRF','MOS','WRF','MOS']]
tuples = list(zip(*arrays))
index = pd.MultiIndex.from_tuples(tuples)
df = pd.DataFrame(np.random.randn(12, 4), index=arrays,
columns=['00 UTC', '06 UTC', '12 UTC', '18 UTC'])
def highlight_MOS(s):
is_mos = s.index.get_level_values(1) == 'MOS'
return ['color: darkorange' if v else 'color: darkblue' for v in is_mos]
s = df.style.apply(highlight_MOS)
s