How do I activate a specific workbook and a specific sheet?

You do not need to activate the sheet (you’ll take a huge performance hit for doing so, actually). Since you are declaring an object for the sheet, when you call the method starting with “wb.” you are selecting that object. For example, you can jump in between workbooks without activating anything like here:

Sub Test()

Dim wb1 As Excel.Workbook
Set wb1 = Workbooks.Open("C:\Documents and Settings\xxxx\Desktop\test1.xls")
Dim wb2 As Excel.Workbook
Set wb2 = Workbooks.Open("C:\Documents and Settings\xxxx\Desktop\test2.xls")

wb1.Sheets("Sheet1").Cells(1, 1).Value = 24
wb2.Sheets("Sheet1").Cells(1, 1).Value = 24
wb1.Sheets("Sheet1").Cells(2, 1).Value = 54

End Sub

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