Memcached vs APC which one should I choose? [closed]

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Memcached is a distributed caching system, whereas APC is non-distributed – and mainly an opcode cache.

If (and only if) you have a web application which has to live on different webservers (loadbalancing), you have to use memcache for distributed caching.
If not, just stick to APC and its cache.

You should always use an opcode cache, which APC is (also APC will get integrated into php6 iirc, so why not start using it now).

You can/should use both for different purposes.

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