YES!

But you can’t do it in the way you may immediately think, because you cant animate or create a transition around the properties you’d otherwise rely on (e.g. display, or changing dimensions and setting to overflow:hidden) in order to correctly hide the element and prevent it from taking up visible space.

Therefore, create an animation for the elements in question, and simply toggle visibility:hidden; after 5 seconds, whilst also setting height and width to zero to prevent the element from still occupying space in the DOM flow.

FIDDLE

CSS

html, body {
    height:100%;
    width:100%;
    margin:0;
    padding:0;
}
#hideMe {
    -moz-animation: cssAnimation 0s ease-in 5s forwards;
    /* Firefox */
    -webkit-animation: cssAnimation 0s ease-in 5s forwards;
    /* Safari and Chrome */
    -o-animation: cssAnimation 0s ease-in 5s forwards;
    /* Opera */
    animation: cssAnimation 0s ease-in 5s forwards;
    -webkit-animation-fill-mode: forwards;
    animation-fill-mode: forwards;
}
@keyframes cssAnimation {
    to {
        width:0;
        height:0;
        overflow:hidden;
    }
}
@-webkit-keyframes cssAnimation {
    to {
        width:0;
        height:0;
        visibility:hidden;
    }
}

HTML

<div id='hideMe'>Wait for it...</div>