Pandas reset index on series to remove multiindex

Just call reset_index():

In [130]: s
Out[130]:
0           1
1999-03-31  SOLD_PRICE   NaN
1999-06-30  SOLD_PRICE   NaN
1999-09-30  SOLD_PRICE   NaN
1999-12-31  SOLD_PRICE     3
2000-03-31  SOLD_PRICE     3
Name: 2, dtype: float64

In [131]: s.reset_index()
Out[131]:
            0           1   2
0  1999-03-31  SOLD_PRICE NaN
1  1999-06-30  SOLD_PRICE NaN
2  1999-09-30  SOLD_PRICE NaN
3  1999-12-31  SOLD_PRICE   3
4  2000-03-31  SOLD_PRICE   3

There are many ways to drop columns:

Call reset_index() twice and specify a column:

In [136]: s.reset_index(0).reset_index(drop=True)
Out[136]:
            0   2
0  1999-03-31 NaN
1  1999-06-30 NaN
2  1999-09-30 NaN
3  1999-12-31   3
4  2000-03-31   3

Delete the column after resetting the index:

In [137]: df = s.reset_index()

In [138]: df
Out[138]:
            0           1   2
0  1999-03-31  SOLD_PRICE NaN
1  1999-06-30  SOLD_PRICE NaN
2  1999-09-30  SOLD_PRICE NaN
3  1999-12-31  SOLD_PRICE   3
4  2000-03-31  SOLD_PRICE   3

In [139]: del df[1]

In [140]: df
Out[140]:
            0   2
0  1999-03-31 NaN
1  1999-06-30 NaN
2  1999-09-30 NaN
3  1999-12-31   3
4  2000-03-31   3

Call drop() after resetting:

In [144]: s.reset_index().drop(1, axis=1)
Out[144]:
            0   2
0  1999-03-31 NaN
1  1999-06-30 NaN
2  1999-09-30 NaN
3  1999-12-31   3
4  2000-03-31   3

Then, after you’ve reset your index, just rename the columns

In [146]: df.columns = ['Date', 'Sales']

In [147]: df
Out[147]:
         Date  Sales
0  1999-03-31    NaN
1  1999-06-30    NaN
2  1999-09-30    NaN
3  1999-12-31      3
4  2000-03-31      3