The first method is slightly better, as the cells being assigned to lays next to each other.
First method:
[ ][ ][ ][ ][ ] ....
^1st assignment
^2nd assignment
[ ][ ][ ][ ][ ] ....
^101st assignment
Second method:
[ ][ ][ ][ ][ ] ....
^1st assignment
^101st assignment
[ ][ ][ ][ ][ ] ....
^2nd assignment